Paroxetine

Overview

Paroxetine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL490).

API suppliers (23)

Suppliers of Paroxetine evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• Zydus Lifesciences LimitedIndia1 active DMF GMP on record
• APITORIA PHARMA PRIVATE LTDIndia1 active DMF GMP on record
• MEDICHEM SASpain1 active DMF GMP on record
• Sun Pharmaceutical Industries LimitedIndia1 active DMF GMP on record
• Zhejiang Huahai Pharmaceutical Co., Ltd.China1 active DMF GMP on record
• WANBURY LTDIndia1 active DMF
• Apotex Inc.Canada1 active DMF
• JUBILANT BIOSYS LTDIndia1 active DMF
• SIGNA SA DE CV1 active DMF
• MATRIX PHARMACORP PRIVATE LTDIndia1 active DMF
• Zhejiang Haisen Pharmaceutical Co., Ltd.China1 active DMF
• GlaxoSmithKline plcUnited Kingdom1 active DMF GMP on record
• RECORDATI ESPANA SL
• ITF CHEMICAL LTDABrazil
• Teva Pharmaceutical Industries Ltd.Israel GMP on record
• DR REDDYS LABORATORIES LTD GMP on record
• TAIZHOU HIGHSUN PHARMACEUTICAL CO LTD
• APOTEX PHARMACHEM INC
• SUMITOMO CHEMICAL CO LTDJapan GMP on record
• ASAHI GLASS CO LTD
• Cadila Healthcare LimitedIndia
• Aesica Pharmaceuticals LimitedUnited Kingdom GMP on record
• CHEMI SPAItaly GMP on record

Patent & exclusivity (US)

Per the FDA Orange Book (64 approved US products), the latest listed US patent on Paroxetine expires 6 Apr 2029. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine

Canonical SMILES

C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4

InChIKey

AHOUBRCZNHFOSL-YOEHRIQHSA-N