Paltusotine

Overview

Paltusotine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL5267842).

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Paltusotine expires 25 Mar 2044 and exclusivity 25 Sept 2032. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

3-[4-(4-aminopiperidin-1-yl)-3-(3,5-difluorophenyl)quinolin-6-yl]-2-hydroxybenzonitrile

Canonical SMILES

C1CN(CCC1N)C2=C3C=C(C=CC3=NC=C2C4=CC(=CC(=C4)F)F)C5=CC=CC(=C5O)C#N

InChIKey

GHILNKWBALQPDP-UHFFFAOYSA-N