Opicapone

CAS 923287-50-7 4 API suppliersSmall Molecule

Overview

Opicapone is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1089318).

API suppliers (4)

Suppliers of Opicapone evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

Where these suppliers are
India2China1

Country recorded for 3 of 4 suppliers.

3 of 4 hold a GMP certificate on record in the EU or UK registers

  • BIAL PORTELA AND CA SA2 active DMF GMP on record
  • MSN LIFE SCIENCES PRIVATE LIMITEDIndia1 active DMF GMP on record
  • Hetero Labs LimitedIndia1 active DMF GMP on record
  • Jiangxi Synergy Pharmaceutical Co., LtdChina1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Opicapone expires 12 Dec 2032. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
5-[3-(2,5-dichloro-4,6-dimethyl-1-oxidopyridin-1-ium-3-yl)-1,2,4-oxadiazol-5-yl]-3-nitrobenzene-1,2-diol
Canonical SMILES
CC1=C(C(=[N+](C(=C1Cl)C)[O-])Cl)C2=NOC(=N2)C3=CC(=C(C(=C3)O)O)[N+](=O)[O-]
InChIKey
ASOADIZOVZTJSR-UHFFFAOYSA-N
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