Nirogacestat
CAS 1290543-63-3Small Molecule
Overview
Nirogacestat is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1770916).
Patent & exclusivity (US)
Per the FDA Orange Book (2 approved US products), the latest listed US patent on Nirogacestat expires 19 May 2043 and exclusivity 27 Nov 2030. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- (2S)-2-[[(2S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl]amino]-N-[1-[1-(2,2-dimethylpropylamino)-2-methylpropan-2-yl]imidazol-4-yl]pentanamide
- Canonical SMILES
- CCC[C@@H](C(=O)NC1=CN(C=N1)C(C)(C)CNCC(C)(C)C)N[C@H]2CCC3=C(C2)C(=CC(=C3)F)F
- InChIKey
- VFCRKLWBYMDAED-REWPJTCUSA-N
Verified Supplier Partner
Do you supply Nirogacestat? Get in front of buyers actively sourcing it.
We route real sourcing requests from pharma buyers to vetted, verified partners — qualified leads, not just a listing. Tell us what you make and we'll be in touch about becoming a Verified Supplier Partner.
Ready to Accelerate Your
Discovery Workflow?
Find, vet, and source drug-manufacturing partners faster — with FDA compliance screening built in. Start free for 7 days.