Nicardipine

Overview

Nicardipine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1484).

API suppliers (7)

Suppliers of Nicardipine backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• CHEMWERTH INC1 active DMF
• CHEMWERTH INC1 active DMF
• NAVINTA LLCUnited States1 active DMF
• LUSOCHIMICA SPAItaly1 active DMF
• CHEMWERTH INC1 active DMF
• NAVINTA LLCUnited States1 active DMF
• LUSOCHIMICA SPAItaly1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (33 approved US products), the latest listed US patent on Nicardipine expires 26 Dec 2027. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Canonical SMILES

CC1=C(C(C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC

InChIKey

ZBBHBTPTTSWHBA-UHFFFAOYSA-N