Netarsudil

Overview

Netarsudil is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL4594250).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Netarsudil expires 14 Mar 2034. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

[4-[(2S)-3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl]phenyl]methyl 2,4-dimethylbenzoate

Canonical SMILES

CC1=CC(=C(C=C1)C(=O)OCC2=CC=C(C=C2)[C@@H](CN)C(=O)NC3=CC4=C(C=C3)C=NC=C4)C

InChIKey

OURRXQUGYQRVML-AREMUKBSSA-N