Nerandomilast

Overview

Nerandomilast is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL5314532).

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Nerandomilast expires 22 Oct 2038 and exclusivity 7 Oct 2032. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

[1-[[2-[4-(5-chloropyrimidin-2-yl)piperidin-1-yl]-5-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl]amino]cyclobutyl]methanol

Canonical SMILES

C1CC(C1)(CO)NC2=NC(=NC3=C2S(=O)CC3)N4CCC(CC4)C5=NC=C(C=N5)Cl

InChIKey

UHYCLWAANUGUMN-UHFFFAOYSA-N