Morphine

Overview

Morphine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL70).

API suppliers (5)

Suppliers of Morphine evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• VERANOVA LPUnited Kingdom1 active DMF
• NORAMCO INCUnited States1 active DMF
• Siegfried LTDUnited Kingdom
• CODY LABORATORIES INC
• MALLINCKRODT INC

Patent & exclusivity (US)

Per the FDA Orange Book (85 approved US products), the latest listed US patent on Morphine expires 12 Mar 2034. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(4R,4aR,7S,7aR,12bS)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol

Canonical SMILES

CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3[C@H](C=C4)O

InChIKey

BQJCRHHNABKAKU-KBQPJGBKSA-N