Mitapivat

Overview

Mitapivat is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL4299940).

Patent & exclusivity (US)

Per the FDA Orange Book (4 approved US products), the latest listed US patent on Mitapivat expires 31 Jul 2041 and exclusivity 23 Dec 2032. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

N-[4-[4-(cyclopropylmethyl)piperazine-1-carbonyl]phenyl]quinoline-8-sulfonamide

Canonical SMILES

C1CC1CN2CCN(CC2)C(=O)C3=CC=C(C=C3)NS(=O)(=O)C4=CC=CC5=C4N=CC=C5

InChIKey

XAYGBKHKBBXDAK-UHFFFAOYSA-N