Metronidazole

Overview

Metronidazole is a nitroimidazole antibiotic medication used for the treatment of anaerobic bacterial and protozoal infections. It acts by inhibiting nucleic acid synthesis by disrupting the DNA of microbial cells.

API suppliers (12)

Suppliers of Metronidazole evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• CORDEN PHARMA BERGAMO SPAItaly1 active DMF GMP on record
• Unichem Laboratories Ltd.India1 active DMF GMP on record
• MEDIMPEX NORTH AMERICA INC
• TIANJIN HEBEI PHARMACEUTICAL FACTORY
• TIANJIN ZHONGAN PHARMACEUTICAL CO LTD
• HUBEI HONGYUAN PHARMACEUTICAL CO LTD
• HEC Pharm USA Inc.United States
• Wuhan Wuyao Pharmaceutical Co., Ltd.China
• RHONE POULENC INC
• COMPANHIA INDUSTRIAL PRODUTORA DE ANTIBIOTICOS SARL
• ZAKLADY FARMACEUTYCZNE POLPHARMA SA
• UNIQUE CHEMICALSIndia

EU CEP holders (3)

Companies holding a valid EU Certificate of Suitability (CEP) for Metronidazole, from the EDQM certification database. A CEP holder is a documented EU-market source of the substance — not necessarily the manufacturer — and these are not yet profiled in our directory.

Patent & exclusivity (US)

Per the FDA Orange Book (58 approved US products), the latest listed US patent on Metronidazole expires 4 Oct 2039. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-(2-methyl-5-nitroimidazol-1-yl)ethanol

Canonical SMILES

CC1=NC=C(N1CCO)[N+](=O)[O-]

InChIKey

VAOCPAMSLUNLGC-UHFFFAOYSA-N

Therapeutic areas