Metronidazole

Overview

Metronidazole is a nitroimidazole antibiotic medication used for the treatment of anaerobic bacterial and protozoal infections. It acts by inhibiting nucleic acid synthesis by disrupting the DNA of microbial cells.

API suppliers (14)

Suppliers of Metronidazole backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• CORDEN PHARMA BERGAMO SPAItaly1 active DMF
• Unichem Laboratories Ltd.India1 active DMF
• Unichem Laboratories Ltd.India1 active DMF
• CORDEN PHARMA BERGAMO SPAItaly1 active DMF
• MEDIMPEX NORTH AMERICA INC
• TIANJIN HEBEI PHARMACEUTICAL FACTORY
• HUBEI HONGYUAN PHARMACEUTICAL CO LTD
• Zakłady Farmaceutyczne Polpharma S.A.Poland
• UNIQUE CHEMICALSIndia
• TIANJIN ZHONGAN PHARMACEUTICAL CO LTD
• RHONE POULENC INC
• WUHAN WUYAO PHARMACEUTICAL CO LTD
• HEC PHARM COChina
• COMPANHIA INDUSTRIAL PRODUTORA DE ANTIBIOTICOS SARL

Patent & exclusivity (US)

Per the FDA Orange Book (58 approved US products), the latest listed US patent on Metronidazole expires 3 Oct 2039. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-(2-methyl-5-nitroimidazol-1-yl)ethanol

Canonical SMILES

CC1=NC=C(N1CCO)[N+](=O)[O-]

InChIKey

VAOCPAMSLUNLGC-UHFFFAOYSA-N

Therapeutic areas