Metronidazole
Overview
Metronidazole is a nitroimidazole antibiotic medication used for the treatment of anaerobic bacterial and protozoal infections. It acts by inhibiting nucleic acid synthesis by disrupting the DNA of microbial cells.
API suppliers (12)
Suppliers of Metronidazole evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.
Country recorded for 5 of 12 suppliers.
2 of 12 hold a GMP certificate on record in the EU or UK registers
- CORDEN PHARMA BERGAMO SPAItaly1 active DMF GMP on record
- Unichem Laboratories Ltd.India1 active DMF GMP on record
- RHONE POULENC INC
- HUBEI HONGYUAN PHARMACEUTICAL CO LTD
- COMPANHIA INDUSTRIAL PRODUTORA DE ANTIBIOTICOS SARL
- UNIQUE CHEMICALSIndia
- MEDIMPEX NORTH AMERICA INC
- TIANJIN HEBEI PHARMACEUTICAL FACTORY
- ZAKLADY FARMACEUTYCZNE POLPHARMA SA
- HEC Pharm USA Inc.United States
- TIANJIN ZHONGAN PHARMACEUTICAL CO LTD
- Wuhan Wuyao Pharmaceutical Co., Ltd.China
Patent & exclusivity (US)
Per the FDA Orange Book (58 approved US products), the latest listed US patent on Metronidazole expires 4 Oct 2039. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- 2-(2-methyl-5-nitroimidazol-1-yl)ethanol
- Canonical SMILES
- CC1=NC=C(N1CCO)[N+](=O)[O-]
- InChIKey
- VAOCPAMSLUNLGC-UHFFFAOYSA-N
Therapeutic areas
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