Mavacamten

Overview

Mavacamten is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL4297517).

API suppliers (12)

Suppliers of Mavacamten evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• MAITHRI DRUGS PRIVATE LTDIndia1 active DMF GMP on record
• APICHEM Laboratories Private LimitedIndia1 active DMF
• MOEHS IBERICA SLSpain1 active DMF GMP on record
• DR REDDYS LABORATORIES LTD1 active DMF GMP on record
• DASAMI LAB PRIVATE LTDIndia1 active DMF GMP on record
• Viyash Scientific LtdIndia1 active DMF GMP on record
• Micro Labs Usa1 active DMF
• XUZHOU WANBANG JINQIAO PHARMA CO LTDChina1 active DMF
• METROCHEM API PRIVATE LTDIndia1 active DMF
• APITORIA PHARMA PRIVATE LTDIndia1 active DMF GMP on record
• TAPI NL BVNetherlands1 active DMF
• BIOPHORE INDIA PHARMACEUTICALS PVT LTD1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (4 approved US products), the latest listed US patent on Mavacamten expires 28 Apr 2036 and exclusivity 28 Apr 2029. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

6-[[(1S)-1-phenylethyl]amino]-3-propan-2-yl-1H-pyrimidine-2,4-dione

Canonical SMILES

C[C@@H](C1=CC=CC=C1)NC2=CC(=O)N(C(=O)N2)C(C)C

InChIKey

RLCLASQCAPXVLM-NSHDSACASA-N