Mavacamten

Overview

Mavacamten is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL4297517).

API suppliers (12)

Suppliers of Mavacamten backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• MOEHS IBERICA SLSpain1 active DMF
• Dr. Reddy's Laboratories Ltd.India1 active DMF
• DASAMI LAB PRIVATE LTDIndia1 active DMF
• MAHIMA LIFE SCIENCES PRIVATE LTDIndia1 active DMF
• MICRO LABS LTDIndia1 active DMF
• TIANISH LABORATORIES PRIVATE LTDIndia1 active DMF
• XUZHOU WANBANG JINQIAO PHARMA CO LTDChina1 active DMF
• METROCHEM API PRIVATE LTDIndia1 active DMF
• APITORIA PHARMA PRIVATE LTDIndia1 active DMF
• TAPI NL BVNetherlands1 active DMF
• Taiji Biopharmaceuticals Pvt. Ltd.India1 active DMF
• MAITHRI DRUGS PRIVATE LTDIndia1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (4 approved US products), the latest listed US patent on Mavacamten expires 28 Apr 2036 and exclusivity 28 Apr 2029. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

6-[[(1S)-1-phenylethyl]amino]-3-propan-2-yl-1H-pyrimidine-2,4-dione

Canonical SMILES

C[C@@H](C1=CC=CC=C1)NC2=CC(=O)N(C(=O)N2)C(C)C

InChIKey

RLCLASQCAPXVLM-NSHDSACASA-N