Lusutrombopag

Overview

Lusutrombopag is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2107831).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Lusutrombopag expires 29 Sept 2031. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(E)-3-[2,6-dichloro-4-[[4-[3-[(1S)-1-hexoxyethyl]-2-methoxyphenyl]-1,3-thiazol-2-yl]carbamoyl]phenyl]-2-methylprop-2-enoic acid

Canonical SMILES

CCCCCCO[C@@H](C)C1=CC=CC(=C1OC)C2=CSC(=N2)NC(=O)C3=CC(=C(C(=C3)Cl)/C=C(\C)/C(=O)O)Cl

InChIKey

NOZIJMHMKORZBA-KJCUYJGMSA-N