Lumateperone

CAS 313368-91-1Small Molecule

Overview

Lumateperone is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3306803).

Patent & exclusivity (US)

Per the FDA Orange Book (3 approved US products), the latest listed US patent on Lumateperone expires 10 Dec 2040 and exclusivity 24 Apr 2029. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
1-(4-fluorophenyl)-4-[(10R,15S)-4-methyl-1,4,12-triazatetracyclo[7.6.1.05,16.010,15]hexadeca-5,7,9(16)-trien-12-yl]butan-1-one
Canonical SMILES
CN1CCN2[C@H]3CCN(C[C@H]3C4=C2C1=CC=C4)CCCC(=O)C5=CC=C(C=C5)F
InChIKey
HOIIHACBCFLJET-SFTDATJTSA-N
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