Loratadine

Overview

Loratadine is a second-generation antihistamine drug used to treat allergic rhinitis and urticaria. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms.

API suppliers (19)

Suppliers of Loratadine evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• VASUDHA PHARMA CHEM LTDIndia2 active DMF
• Zydus Lifesciences LimitedIndia1 active DMF GMP on record
• ALIVUS LIFE SCIENCES LTDIndia1 active DMF GMP on record
• Cadila Pharmaceuticals LimitedIndia1 active DMF GMP on record
• MATRIX PHARMACORP PRIVATE LTDIndia1 active DMF
• MOREPEN LABORATORIES LTDIndia1 active DMF GMP on record
• SOLARA ACTIVE PHARMA SCIENCES LTDIndia1 active DMF GMP on record
• Sun Pharmaceutical Industries LimitedIndia1 active DMF GMP on record
• QUIMICA SINTETICA SASpain1 active DMF GMP on record
• ROLABO OUTSOURCING SLSpain1 active DMF GMP on record
• Divis LaboratoriesIndia GMP on record
• INKE SASpain
• MEDICHEM SASpain GMP on record
• MYLAN LABORATORIES LTD GMP on record
• Cadila Healthcare LimitedIndia
• MSD INTERNATIONAL GMBH GMP on record
• SUZHOU WANQING PHARMACEUTICALS CO LTD
• ZHEJIANG WEPON PHARMACEUTICAL CO LTD
• AARTI DRUGS LTDIndia GMP on record

EU CEP holders (7)

Companies holding a valid EU Certificate of Suitability (CEP) for Loratadine, from the EDQM certification database. A CEP holder is a documented EU-market source of the substance — not necessarily the manufacturer — and these are not yet profiled in our directory.

Chemical identity

IUPAC name

ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate

Canonical SMILES

CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1

InChIKey

JCCNYMKQOSZNPW-UHFFFAOYSA-N

Therapeutic areas