Lifitegrast

Overview

Lifitegrast is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2048028).

API suppliers (13)

Suppliers of Lifitegrast evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• HONOUR LAB LTDIndia1 active DMF GMP on record
• ALIVUS LIFE SCIENCES LTDIndia1 active DMF GMP on record
• MSN LIFE SCIENCES PRIVATE LIMITEDIndia1 active DMF GMP on record
• OLON SPAItaly1 active DMF GMP on record
• APITORIA PHARMA PRIVATE LTDIndia1 active DMF GMP on record
• Sun Pharmaceutical Industries LimitedIndia1 active DMF GMP on record
• Micro Labs Usa1 active DMF
• SCINOPHARM TAIWAN LTDTaiwan1 active DMF
• INTERQUIM SAPeru1 active DMF GMP on record
• Mankind Pharma LimitedIndia1 active DMF GMP on record
• GUANG'AN KINGDAY PHARMA AND CHEM CO LTD1 active DMF
• Viwit Pharmaceutical Co., Ltd.China1 active DMF
• DR REDDYS LABORATORIES LTD1 active DMF GMP on record

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Lifitegrast expires 18 Dec 2033. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(2S)-2-[[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-methylsulfonylphenyl)propanoic acid

Canonical SMILES

CS(=O)(=O)C1=CC=CC(=C1)C[C@@H](C(=O)O)NC(=O)C2=C(C=C3CN(CCC3=C2Cl)C(=O)C4=CC5=C(C=C4)C=CO5)Cl

InChIKey

JFOZKMSJYSPYLN-QHCPKHFHSA-N