Lifitegrast

Overview

Lifitegrast is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2048028).

API suppliers (13)

Suppliers of Lifitegrast backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• Dr. Reddy's Laboratories Ltd.India1 active DMF
• ALIVUS LIFE SCIENCES LTDIndia1 active DMF
• MAHIMA LIFE SCIENCES PRIVATE LTDIndia1 active DMF
• OLON SPAItaly1 active DMF
• APITORIA PHARMA PRIVATE LTDIndia1 active DMF
• Sun Pharmaceutical Industries LimitedIndia1 active DMF
• MICRO LABS LTDIndia1 active DMF
• SCINOPHARM TAIWAN LTDTaiwan1 active DMF
• INTERQUIM SAPeru1 active DMF
• Mankind Pharma LimitedIndia1 active DMF
• GUANG'AN KINGDAY PHARMA AND CHEM CO LTD1 active DMF
• Ono Pharmaceutical Co., Ltd.Japan1 active DMF
• HONOUR LAB LTDIndia1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Lifitegrast expires 18 Dec 2033. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(2S)-2-[[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-methylsulfonylphenyl)propanoic acid

Canonical SMILES

CS(=O)(=O)C1=CC=CC(=C1)C[C@@H](C(=O)O)NC(=O)C2=C(C=C3CN(CCC3=C2Cl)C(=O)C4=CC5=C(C=C4)C=CO5)Cl

InChIKey

JFOZKMSJYSPYLN-QHCPKHFHSA-N