Levoleucovorin

Small Molecule

Overview

Levoleucovorin is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1908841).

Patent & exclusivity (US)

Per the FDA Orange Book (7 approved US products), the latest listed US patent on Levoleucovorin expires 25 Mar 2039. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid
Canonical SMILES
C1[C@@H](N(C2=C(N1)NC(=NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
InChIKey
VVIAGPKUTFNRDU-STQMWFEESA-N

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