Leucovorin
3 API suppliersSmall Molecule
Overview
Leucovorin is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1679).
API suppliers (3)
Suppliers of Leucovorin evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.
- MONSANTO CO
- ORION CORP FARMOS CHEMICAL PLANT
- GMT FINE CHEMCALS SA
Patent & exclusivity (US)
Per the FDA Orange Book (48 approved US products), the latest listed US patent on Leucovorin expires 23 Dec 2044. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- (2S)-2-[[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
- Canonical SMILES
- C1C(N(C2=C(N1)NC(=NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
- InChIKey
- VVIAGPKUTFNRDU-ABLWVSNPSA-N
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