Leniolisib

CAS 1354690-24-6Small Molecule

Overview

Leniolisib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3643413).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Leniolisib expires 19 Feb 2032 and exclusivity 24 Mar 2030. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
1-[(3S)-3-[[6-[6-methoxy-5-(trifluoromethyl)-3-pyridinyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl]amino]pyrrolidin-1-yl]propan-1-one
Canonical SMILES
CCC(=O)N1CC[C@@H](C1)NC2=NC=NC3=C2CN(CC3)C4=CC(=C(N=C4)OC)C(F)(F)F
InChIKey
MWKYMZXCGYXLPL-ZDUSSCGKSA-N
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