Lemborexant

Overview

Lemborexant is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3545367).

API suppliers (2)

Suppliers of Lemborexant backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• MOEHS IBERICA SLSpain1 active DMF
• Sichuan Baili Pharmaceutical Co., Ltd.China1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Lemborexant expires 21 Oct 2035 and exclusivity 20 Apr 2026. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

cis-(1R,2S)-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-2-(3-fluorophenyl)-N-(5-fluoro-2-pyridinyl)cyclopropane-1-carboxamide

Canonical SMILES

CC1=NC(=NC=C1OC[C@]2(C[C@H]2C(=O)NC3=NC=C(C=C3)F)C4=CC(=CC=C4)F)C

InChIKey

MUGXRYIUWFITCP-PGRDOPGGSA-N