Lefamulin
CAS 1061337-51-6Small Molecule
Overview
Lefamulin is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3291398).
Patent & exclusivity (US)
Per the FDA Orange Book (2 approved US products), the latest listed US patent on Lefamulin expires 14 Jun 2036 and exclusivity 19 Aug 2029. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- [(1S,2R,3S,4S,6R,7R,8R,14R)-4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxo-6-tricyclo[5.4.3.01,8]tetradecanyl] 2-[(1R,2R,4R)-4-amino-2-hydroxycyclohexyl]sulfanylacetate
- Canonical SMILES
- C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@@]1([C@@H](C[C@@]([C@H]([C@@H]3C)O)(C)C=C)OC(=O)CS[C@@H]4CC[C@H](C[C@H]4O)N)C
- InChIKey
- KPVIXBKIJXZQJX-FCEONZPQSA-N
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