Iptacopan

Overview

Iptacopan is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL4594448).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Iptacopan expires 15 Jul 2041 and exclusivity 20 Mar 2032. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid

Canonical SMILES

CCO[C@H]1CCN([C@@H](C1)C2=CC=C(C=C2)C(=O)O)CC3=C(C=C(C4=C3C=CN4)C)OC

InChIKey

RENRQMCACQEWFC-UGKGYDQZSA-N