Indocyanine Green
Overview
Indocyanine Green is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1646).
API suppliers (7)
Suppliers of Indocyanine Green evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.
Country recorded for 5 of 7 suppliers.
2 of 7 hold a GMP certificate on record in the EU or UK registers
- ICROM SRLItaly1 active DMF GMP on record
- NANTONG JINGHUA PHARMACEUTICAL CO LTDChina1 active DMF
- HUBEI BIOCAUSE HEILEN PHARMACEUTICAL CO LTDChina1 active DMF
- BIOPHORE INDIA PHARMACEUTICALS PVT LTD1 active DMF
- MACSEN DRUGSIndia1 active DMF
- DISTILLATION PROD INDS DIV EASTMAN KODAK CO
- PCASFrance GMP on record
Patent & exclusivity (US)
Per the FDA Orange Book (6 approved US products), the latest listed US patent on Indocyanine Green expires 14 Jul 2039 and exclusivity 31 Jan 2027. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- sodium 4-[2-[7-[1,1-dimethyl-3-(4-sulfonatobutyl)benzo[e]indol-3-ium-2-yl]hepta-2,4,6-trienylidene]-1,1-dimethylbenzo[e]indol-3-yl]butane-1-sulfonate
- Canonical SMILES
- CC1(C(=[N+](C2=C1C3=CC=CC=C3C=C2)CCCCS(=O)(=O)[O-])C=CC=CC=CC=C4C(C5=C(N4CCCCS(=O)(=O)[O-])C=CC6=CC=CC=C65)(C)C)C.[Na+]
- InChIKey
- MOFVSTNWEDAEEK-UHFFFAOYSA-M
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