Indocyanine Green
Overview
Indocyanine Green is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1646).
API suppliers (7)
Suppliers of Indocyanine Green evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.
Country recorded for 5 of 7 suppliers.
2 of 7 hold a GMP certificate on record in the EU or UK registers
- NANTONG JINGHUA PHARMACEUTICAL CO LTDChina1 active DMF
- HUBEI BIOCAUSE HEILEN PHARMACEUTICAL CO LTDChina1 active DMF
- BIOPHORE INDIA PHARMACEUTICALS PVT LTD1 active DMF
- ICROM SRLItaly1 active DMF GMP on record
- MACSEN DRUGSIndia1 active DMF
- DISTILLATION PROD INDS DIV EASTMAN KODAK CO
- PCASFrance GMP on record
Patent & exclusivity (US)
Per the FDA Orange Book (4 approved US products), the latest listed US patent on Indocyanine Green expires 14 Jul 2039 and exclusivity 5 Jun 2026. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- sodium 4-[2-[7-[1,1-dimethyl-3-(4-sulfonatobutyl)benzo[e]indol-3-ium-2-yl]hepta-2,4,6-trienylidene]-1,1-dimethylbenzo[e]indol-3-yl]butane-1-sulfonate
- Canonical SMILES
- CC1(C(=[N+](C2=C1C3=CC=CC=C3C=C2)CCCCS(=O)(=O)[O-])C=CC=CC=CC=C4C(C5=C(N4CCCCS(=O)(=O)[O-])C=CC6=CC=CC=C65)(C)C)C.[Na+]
- InChIKey
- MOFVSTNWEDAEEK-UHFFFAOYSA-M
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