Inavolisib

Overview

Inavolisib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL4650215).

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Inavolisib expires 14 Jun 2038 and exclusivity 10 Oct 2029. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(2S)-2-[[2-[(4S)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]amino]propanamide

Canonical SMILES

C[C@@H](C(=O)N)NC1=CC2=C(C=C1)C3=NC(=CN3CCO2)N4[C@@H](COC4=O)C(F)F

InChIKey

SGEUNORSOZVTOL-CABZTGNLSA-N