Ibuprofen

Overview

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) commonly used for relief of pain, fever, and inflammation. It works by inhibiting the production of prostaglandins, substances in the body responsible for inflammation and pain.

API suppliers (30)

Suppliers of Ibuprofen evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• Iol Chemicals And Pharmaceuticals LimitedIndia1 active DMF GMP on record
• LUNA CHEMICAL INDUSTRIES PVT LTD1 active DMF
• BASF PLCFrance1 active DMF
• SMS Pharmaceuticals limitedIndia1 active DMF GMP on record
• SI GROUPUnited States1 active DMF
• SOLARA ACTIVE PHARMA SCIENCES LTDIndia1 active DMF GMP on record
• SHANDONG XINHUA PHARMACEUTICAL CO LTDChina1 active DMF GMP on record
• HUBEI BIOCAUSE HEILEN PHARMACEUTICAL CO LTDChina1 active DMF
• ZIBO XINHUA PERRIGO PHARMACEUTICAL CO LTD1 active DMF GMP on record
• YONEZAWA HAMARI CHEMICALS LTD
• Cipla USA, Inc.USA
• ZAMBON GROUP SPA
• ANTIBIOTICOS SPA
• HEXAGON LABORATORIES INC
• ETHYL CHEMICALS GROUPS
• DR REDDYS LABORATORIES LTD GMP on record
• ARCH PHARMALABS LTDIndia
• CHANDRA PHARMACEUTICALS LTD
• SUMITRA PHARMACEUTICALS AND CHEMICALS LTD
• UNITED BREWERIES LTD
• SHANDONG XIN HUA PHARMACEUTICAL FACTORY
• JUHUA GROUP CORP PHARMACEUTICAL FACTORY
• Piramal Pharma LimitedIndiaCEP GMP on record
• Piramal Enterprises LimitedIndia
• KNOLL PHARMA CHEMICALS

Showing 25 of 30 suppliers — see the full list in the app.

Patent & exclusivity (US)

Per the FDA Orange Book (104 approved US products), the latest listed US patent on Ibuprofen expires 16 Mar 2032 and exclusivity 11 May 2026. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-[4-(2-methylpropyl)phenyl]propanoic acid

Canonical SMILES

CC(C)CC1=CC=C(C=C1)C(C)C(=O)O

InChIKey

HEFNNWSXXWATRW-UHFFFAOYSA-N

Therapeutic areas