Ibuprofen

Overview

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) commonly used for relief of pain, fever, and inflammation. It works by inhibiting the production of prostaglandins, substances in the body responsible for inflammation and pain.

API suppliers (30)

Suppliers of Ibuprofen evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• SMS Pharmaceuticals limitedIndia1 active DMF GMP on record
• SI GROUPUnited States1 active DMF
• SOLARA ACTIVE PHARMA SCIENCES LTDIndia1 active DMF GMP on record
• BASF PLCFrance1 active DMF
• SHANDONG XINHUA PHARMACEUTICAL CO LTDChina1 active DMF GMP on record
• HUBEI BIOCAUSE HEILEN PHARMACEUTICAL CO LTDChina1 active DMF
• ZIBO XINHUA PERRIGO PHARMACEUTICAL CO LTD1 active DMF
• Iol Chemicals And Pharmaceuticals LimitedIndia1 active DMF GMP on record
• LUNA CHEMICAL INDUSTRIES PVT LTD1 active DMF
• YONEZAWA HAMARI CHEMICALS LTD
• Cipla USA, Inc.USA
• HEXAGON LABORATORIES INC
• ETHYL CHEMICALS GROUPS
• JUHUA GROUP CORP PHARMACEUTICAL FACTORY
• CHANDRA PHARMACEUTICALS LTD
• ZAMBON GROUP SPA
• SUMITRA PHARMACEUTICALS AND CHEMICALS LTD
• ARCH PHARMALABS LTDIndia
• UNITED BREWERIES LTD
• SHANDONG XIN HUA PHARMACEUTICAL FACTORY
• Piramal Enterprises LimitedIndia
• ANTIBIOTICOS SPA
• ETHYL CORP
• INDUSTRIAS QUIMICAS ESTEVE SA
• Orion CorporationFinland

Showing 25 of 30 suppliers — see the full list in the app.

EU CEP holders (8)

Companies holding a valid EU Certificate of Suitability (CEP) for Ibuprofen, from the EDQM certification database. A CEP holder is a documented EU-market source of the substance — not necessarily the manufacturer — and these are not yet profiled in our directory.

Patent & exclusivity (US)

Per the FDA Orange Book (105 approved US products), the latest listed US patent on Ibuprofen expires 16 Mar 2032 and exclusivity 11 May 2026. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-[4-(2-methylpropyl)phenyl]propanoic acid

Canonical SMILES

CC(C)CC1=CC=C(C=C1)C(C)C(=O)O

InChIKey

HEFNNWSXXWATRW-UHFFFAOYSA-N

Therapeutic areas