Ibuprofen

Overview

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) commonly used for relief of pain, fever, and inflammation. It works by inhibiting the production of prostaglandins, substances in the body responsible for inflammation and pain.

API suppliers (35)

Suppliers of Ibuprofen backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• SOLARA ACTIVE PHARMA SCIENCES LTD3 active DMF
• JBC Pharmaceuticals Ltd.United Kingdom2 active DMF
• SHANDONG XINHUA PHARMACEUTICAL CO LTDChina2 active DMF
• HUBEI BIOCAUSE HEILEN PHARMACEUTICAL CO LTDChina1 active DMF
• SI GROUPUnited States1 active DMF
• ZIBO XINHUA PERRIGO PHARMACEUTICAL CO LTD1 active DMF
• HUBEI BIOCAUSE HEILEN PHARMACEUTICAL CO LTDChina1 active DMF
• BASF PLC1 active DMF
• SI GROUPUnited States1 active DMF
• HUBEI BIOCAUSE HEILEN PHARMACEUTICAL CO LTDChina1 active DMF
• ZIBO XINHUA PERRIGO PHARMACEUTICAL CO LTD1 active DMF
• ZIBO XINHUA PERRIGO PHARMACEUTICAL CO LTD1 active DMF
• SI GROUPUnited States1 active DMF
• ZIBO XINHUA PERRIGO PHARMACEUTICAL CO LTD1 active DMF
• J.B. Chemicals & Pharmaceuticals Ltd.India1 active DMF
• BLASCHIM SPA
• INDUSTRIA CHEMICA PRODOTTI FRANCIS SPA
• INDUSTRIAS QUIMICAS ESTEVE SA
• YONEZAWA HAMARI CHEMICALS LTD
• Cipla USA, Inc.USA
• ZAMBON SPA
• ANTIBIOTICOS SPA
• HEXAGON LABORATORIES INC
• Dr. Reddy's Laboratories Ltd.India
• ETHYL CHEMICALS GROUPS

Showing 25 of 35 suppliers — see the full list in the app.

Patent & exclusivity (US)

Per the FDA Orange Book (104 approved US products), the latest listed US patent on Ibuprofen expires 16 Mar 2032 and exclusivity 10 May 2026. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-[4-(2-methylpropyl)phenyl]propanoic acid

Canonical SMILES

CC(C)CC1=CC=C(C=C1)C(C)C(=O)O

InChIKey

HEFNNWSXXWATRW-UHFFFAOYSA-N

Therapeutic areas