Hydrocodone

CAS 125-29-1 11 API suppliersSmall Molecule

Overview

Hydrocodone is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1457).

API suppliers (11)

Suppliers of Hydrocodone evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

Where these suppliers are
United States4United Kingdom2

Country recorded for 6 of 11 suppliers.

  • NORAMCO INCUnited States2 active DMF
  • Siegfried LTDUnited Kingdom1 active DMF
  • CHATTEM CHEMICALS INCUnited States1 active DMF
  • VERANOVA LPUnited Kingdom1 active DMF
  • CAMBREX CHARLES CITY INCUnited States1 active DMF
  • SPECGX LLCUnited States1 active DMF
  • CODY LABORATORIES INC
  • JOHNSON MATTHEY PHARMACEUTICAL MATERIALS
  • PENCO OF LYNDHURST INC
  • CODY LABORATORIES INC A WHOLLY OWNED SUBSIDIARY OF LANNETT CO INC
  • WATSON LABORATORIES INC

Patent & exclusivity (US)

Per the FDA Orange Book (19 approved US products), the latest listed US patent on Hydrocodone expires 21 Dec 2031. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
(4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Canonical SMILES
CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3C(=O)CC4
InChIKey
LLPOLZWFYMWNKH-CMKMFDCUSA-N
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