Hydrochlorothiazide

Overview

Hydrochlorothiazide is a diuretic medication used to treat high blood pressure and swelling due to fluid build-up. It helps reduce excess fluid in the body and aids in lowering blood pressure.

API suppliers (21)

Suppliers of Hydrochlorothiazide evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• Ipca Laboratories LimitedIndia2 active DMF GMP on record
• Unichem Laboratories Ltd.India2 active DMF GMP on record
• TAPI NL BVNetherlands2 active DMF
• CTX LIFE SCIENCES PVT LTDIndia1 active DMF
• Zydus Lifesciences LimitedIndia1 active DMF GMP on record
• Alembic Pharmaceuticals LimitedIndia1 active DMF GMP on record
• Zhejiang Huahai Pharmaceutical Co., Ltd.China1 active DMF GMP on record
• AMOLI ORGANICS (A DIVISION OF UMEDICA LABORATORIES PVT LTD)India1 active DMF
• CAMBREX PROFARMACO MILANO SRLItaly1 active DMF GMP on record
• ZAKLADY FARMACEUTYCZNE POLPHARMA SA1 active DMF
• APITORIA PHARMA PRIVATE LTDIndia1 active DMF GMP on record
• VALENS MOLECULES PRIVATE LTDIndia1 active DMF
• Macleods Pharmaceuticals Ltd.India1 active DMF GMP on record
• CHANGZHOU PHARMACEUTICAL FACTORYChina1 active DMF GMP on record
• Laurus Labs LimitedIndia1 active DMF GMP on record
• ABBOTT LABORATORIES PHARMACEUTICAL PRODUCTS DIV
• CHINOIN PHARMACEUTCIAL AND CHEMICAL WORKS CO LTD
• SMITHKLINE AND BECKMAN INC
• LABORATORIOS JULIAN DE MEXICO SA
• Suzhou Lixin Pharmaceutical Co., Ltd.China GMP on record
• MICRO CHEMS LTD

Patent & exclusivity (US)

Per the FDA Orange Book (29 approved US products), the latest listed US patent on Hydrochlorothiazide expires 23 Jan 2044. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide

Canonical SMILES

C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl

InChIKey

JZUFKLXOESDKRF-UHFFFAOYSA-N

Therapeutic areas