Hydrochlorothiazide

Overview

Hydrochlorothiazide is a diuretic medication used to treat high blood pressure and swelling due to fluid build-up. It helps reduce excess fluid in the body and aids in lowering blood pressure.

API suppliers (21)

Suppliers of Hydrochlorothiazide evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• TAPI NL BVNetherlands2 active DMF
• Ipca Laboratories LimitedIndia2 active DMF GMP on record
• Unichem Laboratories Ltd.India2 active DMF GMP on record
• Laurus Labs LimitedIndia1 active DMF GMP on record
• CHANGZHOU PHARMACEUTICAL FACTORYChina1 active DMF GMP on record
• AMOLI ORGANICS (A DIVISION OF UMEDICA LABORATORIES PVT LTD)India1 active DMF
• Zydus Lifesciences LimitedIndia1 active DMF GMP on record
• Alembic Pharmaceuticals LimitedIndia1 active DMF GMP on record
• Zhejiang Huahai Pharmaceutical Co., Ltd.China1 active DMF GMP on record
• Macleods Pharmaceuticals Ltd.India1 active DMF GMP on record
• CAMBREX PROFARMACO MILANO SRLItaly1 active DMF GMP on record
• APITORIA PHARMA PRIVATE LTDIndia1 active DMF GMP on record
• ZAKLADY FARMACEUTYCZNE POLPHARMA SA1 active DMF
• VALENS MOLECULES PRIVATE LTDIndia1 active DMF
• CTX LIFE SCIENCES PVT LTDIndia1 active DMF
• ABBOTT LABORATORIES PHARMACEUTICAL PRODUCTS DIV
• SMITHKLINE AND BECKMAN INC
• CHINOIN PHARMACEUTCIAL AND CHEMICAL WORKS CO LTD
• Suzhou Lixin Pharmaceutical Co., Ltd.China
• MICRO CHEMS LTD
• LABORATORIOS JULIAN DE MEXICO SA

EU CEP holders (10)

Companies holding a valid EU Certificate of Suitability (CEP) for Hydrochlorothiazide, from the EDQM certification database. A CEP holder is a documented EU-market source of the substance — not necessarily the manufacturer — and these are not yet profiled in our directory.

Patent & exclusivity (US)

Per the FDA Orange Book (29 approved US products), the latest listed US patent on Hydrochlorothiazide expires 23 Jan 2044. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide

Canonical SMILES

C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl

InChIKey

JZUFKLXOESDKRF-UHFFFAOYSA-N

Therapeutic areas