Halobetasol Propionate

Overview

Halobetasol Propionate is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1200908).

API suppliers (8)

Suppliers of Halobetasol Propionate evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• Hovione FarmaCiencia SAPortugal1 active DMF GMP on record
• TRIFARMA SPAItaly1 active DMF GMP on record
• SYMBIOTICA SPECIALITY INGREDIENTS SDN BHDMalaysia1 active DMF
• SYMBIOTEC PHARMALAB LTD1 active DMF GMP on record
• WAVELENGTH ENTERPRISES LTDIsrael1 active DMF GMP on record
• STERLING SPAItaly1 active DMF GMP on record
• Taro Pharmaceutical Industries Ltd.Israel1 active DMF GMP on record
• Teva Pharmaceutical Industries Ltd.Israel GMP on record

Patent & exclusivity (US)

Per the FDA Orange Book (10 approved US products), the latest listed US patent on Halobetasol Propionate expires 19 Jun 2033. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate

Canonical SMILES

CCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O)C)C)C(=O)CCl

InChIKey

BDSYKGHYMJNPAB-LICBFIPMSA-N