Halobetasol Propionate

Overview

Halobetasol Propionate is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1200908).

API suppliers (18)

Suppliers of Halobetasol Propionate backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• STERLING SPAItaly1 active DMF
• WAVELENGTH ENTERPRISES LTDIsrael1 active DMF
• Taro Pharmaceutical Industries Ltd.Israel1 active DMF
• STERLING SPAItaly1 active DMF
• TRIFARMA SPA1 active DMF
• Taro Pharmaceutical Industries Ltd.Israel1 active DMF
• Hovione FarmaCiencia SAPortugal1 active DMF
• WAVELENGTH ENTERPRISES LTDIsrael1 active DMF
• SYMBIOTEC PHARMALAB PRIVATE LTD1 active DMF
• TRIFARMA SPA1 active DMF
• Taro Pharmaceutical Industries Ltd.Israel1 active DMF
• Hovione FarmaCiencia SAPortugal1 active DMF
• TRIFARMA SPA1 active DMF
• SYMBIOTEC PHARMALAB PRIVATE LTD1 active DMF
• Taro Pharmaceutical Industries Ltd.Israel1 active DMF
• Hovione FarmaCiencia SAPortugal1 active DMF
• TRIFARMA SPA1 active DMF
• SYMBIOTEC PHARMALAB PRIVATE LTD1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (9 approved US products), the latest listed US patent on Halobetasol Propionate expires 18 Jun 2033. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate

Canonical SMILES

CCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O)C)C)C(=O)CCl

InChIKey

BDSYKGHYMJNPAB-LICBFIPMSA-N