Glasdegib

Overview

Glasdegib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2043437).

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Glasdegib expires 13 Apr 2036. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

1-[(2R,4R)-2-(1H-benzimidazol-2-yl)-1-methylpiperidin-4-yl]-3-(4-cyanophenyl)urea

Canonical SMILES

CN1CC[C@H](C[C@@H]1C2=NC3=CC=CC=C3N2)NC(=O)NC4=CC=C(C=C4)C#N

InChIKey

SFNSLLSYNZWZQG-VQIMIIECSA-N