Ganaxolone

Overview

Ganaxolone is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1568698).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Ganaxolone expires 29 Sept 2042 and exclusivity 31 May 2029. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

1-[(3R,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-3,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]ethanone

Canonical SMILES

CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@@](C4)(C)O)C)C

InChIKey

PGTVWKLGGCQMBR-FLBATMFCSA-N