Futibatinib

CAS 1448169-71-8Small Molecule

Overview

Futibatinib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3701238).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Futibatinib expires 5 Nov 2039 and exclusivity 30 Sept 2029. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
Canonical SMILES
COC1=CC(=CC(=C1)C#CC2=NN(C3=NC=NC(=C23)N)[C@H]4CCN(C4)C(=O)C=C)OC
InChIKey
KEIPNCCJPRMIAX-HNNXBMFYSA-N
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