Fostemsavir Tromethamine

Overview

Fostemsavir Tromethamine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3301598).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Fostemsavir Tromethamine expires 13 Jul 2029. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-amino-2-(hydroxymethyl)propane-1,3-diol;[3-[2-(4-benzoylpiperazin-1-yl)-2-oxoacetyl]-4-methoxy-7-(3-methyl-1,2,4-triazol-1-yl)pyrrolo[2,3-c]pyridin-1-yl]methyl dihydrogen phosphate

Canonical SMILES

CC1=NN(C=N1)C2=NC=C(C3=C2N(C=C3C(=O)C(=O)N4CCN(CC4)C(=O)C5=CC=CC=C5)COP(=O)(O)O)OC.C(C(CO)(CO)N)O

InChIKey

RRGJSMBMTOKHTE-UHFFFAOYSA-N