Fosdenopterin

Small Molecule

Overview

Fosdenopterin is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2338675).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Fosdenopterin expires 9 Apr 2029 and exclusivity 26 Feb 2028. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
(1R,10R,12S,17R)-5-amino-11,11,14-trihydroxy-14-oxo-13,15,18-trioxa-2,4,6,9-tetraza-14lambda5-phosphatetracyclo[8.8.0.03,8.012,17]octadeca-3(8),5-dien-7-one
Canonical SMILES
C1[C@@H]2[C@@H](C([C@H]3[C@@H](O2)NC4=C(N3)C(=O)N=C(N4)N)(O)O)OP(=O)(O1)O
InChIKey
CZAKJJUNKNPTTO-AJFJRRQVSA-N

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