Fluticasone Furoate

Overview

Fluticasone Furoate is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1676).

API suppliers (13)

Suppliers of Fluticasone Furoate evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• CORAL DRUGS PRIVATE LTD1 active DMF GMP on record
• STERLING SPAItaly1 active DMF GMP on record
• WAVELENGTH ENTERPRISES LTDIsrael1 active DMF GMP on record
• GlaxoSmithKline plcUnited Kingdom1 active DMF GMP on record
• Aurisco Pharmaceutical Co.,ltdChina1 active DMF GMP on record
• AARTI PHARMALABS LIMITEDIndia1 active DMF
• TAPI NL BVNetherlands1 active DMF
• Cipla USA, Inc.USA1 active DMF
• Lupin LimitedIndia1 active DMF GMP on record
• FARMABIOS SPAItaly1 active DMF
• NEWCHEM SPAItaly1 active DMF GMP on record
• SHANDONG RISEN-SUN PHARMACEUTICAL CO LTD1 active DMF
• VAMSI LABS LTDIndia GMP on record

Patent & exclusivity (US)

Per the FDA Orange Book (4 approved US products), the latest listed US patent on Fluticasone Furoate expires 15 Oct 2028 and exclusivity 1 Mar 2026. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] furan-2-carboxylate

Canonical SMILES

C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)SCF)OC(=O)C5=CC=CO5)C)O)F)C)F

InChIKey

XTULMSXFIHGYFS-VLSRWLAYSA-N