Fluocinolone Acetonide

Overview

Fluocinolone Acetonide is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL989).

API suppliers (8)

Suppliers of Fluocinolone Acetonide backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• FARMABIOS SPA1 active DMF
• FARMABIOS SPA1 active DMF
• FARMABIOS SPA1 active DMF
• QUATRUM
• Dr. Reddy's Laboratories Ltd.India
• ANTIBIOTICOS SPA
• FARMABOIS
• NOBEL CHEMICALS AB DIV FINE CHEMICALS INC

Patent & exclusivity (US)

Per the FDA Orange Book (37 approved US products), the latest listed US patent on Fluocinolone Acetonide expires 7 Nov 2028. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one

Canonical SMILES

C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)CO)C[C@@H](C5=CC(=O)C=C[C@@]53C)F)F)O

InChIKey

FEBLZLNTKCEFIT-VSXGLTOVSA-N