Fluocinolone Acetonide

CAS 67-73-2 7 API suppliersSmall Molecule

Overview

Fluocinolone Acetonide is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL989).

API suppliers (7)

Suppliers of Fluocinolone Acetonide evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

Where these suppliers are
Italy1

Country recorded for 1 of 7 suppliers.

1 of 7 holds a GMP certificate on record in the EU or UK registers

Patent & exclusivity (US)

Per the FDA Orange Book (36 approved US products), the latest listed US patent on Fluocinolone Acetonide expires 7 Nov 2028. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
(1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
Canonical SMILES
C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)CO)C[C@@H](C5=CC(=O)C=C[C@@]53C)F)F)O
InChIKey
FEBLZLNTKCEFIT-VSXGLTOVSA-N
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