Febuxostat

Overview

Febuxostat is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1164729).

API suppliers (24)

Suppliers of Febuxostat evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• DR REDDYS LABORATORIES LTD1 active DMF GMP on record
• CHONGQING SHENGHUAXI PHARMACEUTICAL CO LTD1 active DMF
• Alembic Pharmaceuticals LimitedIndia1 active DMF GMP on record
• AMI LIFESCIENCES PRIVATE LTDIndia1 active DMF GMP on record
• DASAMI LAB PRIVATE LTDIndia1 active DMF GMP on record
• LINHAI TIANYU PHARMACEUTICAL CO LTDChina1 active DMF
• Sun Pharmaceutical Industries LimitedIndia1 active DMF GMP on record
• MATRIX PHARMACORP PRIVATE LTDIndia1 active DMF
• Emcure Pharmaceuticals LimitedIndia1 active DMF GMP on record
• Zhejiang Huahai Pharmaceutical Co., Ltd.China1 active DMF GMP on record
• Macleods Pharmaceuticals Ltd.India1 active DMF GMP on record
• INDOCO REMEDIES LTDIndia1 active DMF GMP on record
• TAPI NL BVNetherlands1 active DMF
• Zhejiang Ausun Pharmaceutical Co., Ltd.China1 active DMF GMP on record
• JUBILANT BIOSYS LTDIndia1 active DMF
• MSN Organics Private LimitedIndia1 active DMF
• APITORIA PHARMA PRIVATE LTDIndia1 active DMF GMP on record
• WANBANG BIOPHARMACEUTICALS1 active DMF GMP on record
• Jiangxi Synergy Pharmaceutical Co., LtdChina1 active DMF
• Torrent PharmaceuticalsIndia1 active DMF GMP on record
• METROCHEM API PRIVATE LTDIndia1 active DMF
• WATERSTONE PHARMACEUTICALS (HUBEI) CO LTDChina
• SIGNA SA DE CV
• ALP PHARM BEIJING CO LTD

Patent & exclusivity (US)

Per the FDA Orange Book (26 approved US products), the latest listed US patent on Febuxostat expires 8 Sept 2031. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid

Canonical SMILES

CC1=C(SC(=N1)C2=CC(=C(C=C2)OCC(C)C)C#N)C(=O)O

InChIKey

BQSJTQLCZDPROO-UHFFFAOYSA-N