Esketamine
Overview
Esketamine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL395091).
API suppliers (1)
Suppliers of Esketamine evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.
1 of 1 holds a GMP certificate on record in the EU or UK registers
- CU CHEMIE UETIKON GMBHGermany1 active DMF GMP on record
Patent & exclusivity (US)
Per the FDA Orange Book (1 approved US product), the latest listed US patent on Esketamine expires 18 Feb 2040 and exclusivity 17 Jan 2028. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- (2S)-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one
- Canonical SMILES
- CN[C@@]1(CCCCC1=O)C2=CC=CC=C2Cl
- InChIKey
- YQEZLKZALYSWHR-ZDUSSCGKSA-N
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