Ensitrelvir

Overview

Ensitrelvir is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL5183847).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Ensitrelvir expires 1 May 2042 and exclusivity 29 May 2031. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

6-[(6-chloro-2-methylindazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[(2,4,5-trifluorophenyl)methyl]-1,3,5-triazine-2,4-dione

Canonical SMILES

CN1C=C2C=C(C(=CC2=N1)Cl)NC3=NC(=O)N(C(=O)N3CC4=CC(=C(C=C4F)F)F)CC5=NN(C=N5)C

InChIKey

QMPBBNUOBOFBFS-UHFFFAOYSA-N