Enasidenib

Overview

Enasidenib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3989908).

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Enasidenib expires 16 Sept 2034. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-methyl-1-[[4-[6-(trifluoromethyl)-2-pyridinyl]-6-[[2-(trifluoromethyl)-4-pyridinyl]amino]-1,3,5-triazin-2-yl]amino]propan-2-ol

Canonical SMILES

CC(C)(CNC1=NC(=NC(=N1)C2=NC(=CC=C2)C(F)(F)F)NC3=CC(=NC=C3)C(F)(F)F)O

InChIKey

DYLUUSLLRIQKOE-UHFFFAOYSA-N