Eluxadoline

Overview

Eluxadoline is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2159122).

API suppliers (6)

Suppliers of Eluxadoline evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• Alkem Laboratories LimitedIndia1 active DMF GMP on record
• LEE PHARMA LTDIndia1 active DMF GMP on record
• Sun Pharmaceutical Industries LimitedIndia1 active DMF GMP on record
• MSN LIFE SCIENCES PRIVATE LIMITEDIndia1 active DMF GMP on record
• HONOUR LAB LTDIndia1 active DMF GMP on record
• APITORIA PHARMA PRIVATE LTDIndia1 active DMF GMP on record

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Eluxadoline expires 14 Mar 2033. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

5-[[[(2S)-2-amino-3-(4-carbamoyl-2,6-dimethylphenyl)propanoyl]-[(1S)-1-(5-phenyl-1H-imidazol-2-yl)ethyl]amino]methyl]-2-methoxybenzoic acid

Canonical SMILES

CC1=CC(=CC(=C1C[C@@H](C(=O)N(CC2=CC(=C(C=C2)OC)C(=O)O)[C@@H](C)C3=NC=C(N3)C4=CC=CC=C4)N)C)C(=O)N

InChIKey

QFNHIDANIVGXPE-FNZWTVRRSA-N