Elamipretide

CAS 736992-21-5Protein

Overview

Elamipretide is a protein active pharmaceutical ingredient (ChEMBL CHEMBL3833370).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Elamipretide expires 28 Feb 2034 and exclusivity 19 Sept 2032. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
(2S)-6-amino-2-[[(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]hexanamide
Canonical SMILES
CC1=CC(=CC(=C1C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N)NC(=O)[C@@H](CCCN=C(N)N)N)C)O
InChIKey
SFVLTCAESLKEHH-WKAQUBQDSA-N
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