Elagolix

Overview

Elagolix is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1208155).

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Elagolix expires 26 Aug 2040. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-4-methyl-2,6-dioxopyrimidin-1-yl]-1-phenylethyl]amino]butanoic acid

Canonical SMILES

CC1=C(C(=O)N(C(=O)N1CC2=C(C=CC=C2F)C(F)(F)F)C[C@@H](C3=CC=CC=C3)NCCCC(=O)O)C4=C(C(=CC=C4)OC)F

InChIKey

HEAUOKZIVMZVQL-VWLOTQADSA-N