Efinaconazole

Overview

Efinaconazole is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2103877).

API suppliers (16)

Suppliers of Efinaconazole evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• TOPHARMAN SHANDONG CO LTDChina1 active DMF
• Cipla USA, Inc.USA1 active DMF
• KAKEN Pharmaceutical Co., LTDJapan1 active DMF GMP on record
• WAVELENGTH ENTERPRISES LTDIsrael1 active DMF GMP on record
• ALIVUS LIFE SCIENCES LTDIndia1 active DMF GMP on record
• VIRUPAKSHA ORGANICS LTDIndia1 active DMF
• LUPIN MANUFACTURING SOLUTIONS LTD1 active DMF
• Dipharma Francis SrlItaly1 active DMF GMP on record
• PROCOS SPAItaly1 active DMF GMP on record
• HARMAN FINOCHEM LTDIndia1 active DMF GMP on record
• Zhejiang Ausun Pharmaceutical Co., Ltd.China1 active DMF GMP on record
• SOLARA ACTIVE PHARMA SCIENCES LTDIndia1 active DMF GMP on record
• Macleods Pharmaceuticals Ltd.India1 active DMF GMP on record
• MATRIX PHARMACORP PRIVATE LTDIndia1 active DMF
• Viwit Pharmaceutical Co., Ltd.China1 active DMF
• SHENZHEN HAIBIN PHARMACEUTICAL CO LTD1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (4 approved US products), the latest listed US patent on Efinaconazole expires 25 Apr 2035. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol

Canonical SMILES

C[C@H]([C@](CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3CCC(=C)CC3

InChIKey

NFEZZTICAUWDHU-RDTXWAMCSA-N