Efinaconazole

Overview

Efinaconazole is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2103877).

API suppliers (16)

Suppliers of Efinaconazole backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• MATRIX PHARMACORP PRIVATE LTDIndia1 active DMF
• Ono Pharmaceutical Co., Ltd.Japan1 active DMF
• Shenzhen Salubris Pharmaceuticals Co., Ltd.China1 active DMF
• TOPHARMAN SHANDONG CO LTDChina1 active DMF
• Kangmei Pharmaceutical Co., Ltd.China1 active DMF
• WAVELENGTH ENTERPRISES LTDIsrael1 active DMF
• ALIVUS LIFE SCIENCES LTDIndia1 active DMF
• VIRUPAKSHA ORGANICS LTDIndia1 active DMF
• LUPIN MANUFACTURING SOLUTIONS LTD1 active DMF
• Dipharma Francis SrlItaly1 active DMF
• PROCOS SPAItaly1 active DMF
• HARMAN FINOCHEM LTDIndia1 active DMF
• Zhejiang Hisun Pharmaceutical Co., Ltd.China1 active DMF
• SOLARA ACTIVE PHARMA SCIENCES LTDIndia1 active DMF
• Cipla USA, Inc.USA1 active DMF
• Macleods Pharmaceuticals Ltd.India1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (4 approved US products), the latest listed US patent on Efinaconazole expires 25 Apr 2035. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol

Canonical SMILES

C[C@H]([C@](CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3CCC(=C)CC3

InChIKey

NFEZZTICAUWDHU-RDTXWAMCSA-N