Edoxaban

Overview

Edoxaban is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1269025).

API suppliers (2)

Suppliers of Edoxaban backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• MAHIMA LIFE SCIENCES PRIVATE LTD2 active DMF
• Zhejiang Hisun Pharmaceutical Co., Ltd.China1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (3 approved US products), the latest listed US patent on Edoxaban expires 27 Mar 2028 and exclusivity 17 Oct 2026. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

N'-(5-chloro-2-pyridinyl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide

Canonical SMILES

CN1CCC2=C(C1)SC(=N2)C(=O)N[C@@H]3C[C@H](CC[C@@H]3NC(=O)C(=O)NC4=NC=C(C=C4)Cl)C(=O)N(C)C

InChIKey

HGVDHZBSSITLCT-JLJPHGGASA-N