Edaravone

Overview

Edaravone is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL290916).

API suppliers (12)

Suppliers of Edaravone evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• ZHEJIANG KINGLAND PHARMACEUTICAL CO LTD1 active DMF
• SOLARA ACTIVE PHARMA SCIENCES LTDIndia1 active DMF GMP on record
• MSN Laboratories Private LimitedIndia1 active DMF GMP on record
• QUIMICA SINTETICA SASpain1 active DMF GMP on record
• GLAND PHARMA LTDIndia1 active DMF GMP on record
• Neuland Laboratories LimitedIndia1 active DMF
• MEDICHEM MANUFACTURING (MALTA) LTDMalta1 active DMF GMP on record
• Cipla USA, Inc.USA1 active DMF
• YUNG ZIP CHEMICAL IND CO LTD1 active DMF
• INTERQUIM SAPeru1 active DMF GMP on record
• BIOPHORE INDIA PHARMACEUTICALS PVT LTD1 active DMF
• DR REDDYS LABORATORIES LTD1 active DMF GMP on record

Patent & exclusivity (US)

Per the FDA Orange Book (4 approved US products), the latest listed US patent on Edaravone expires 12 Nov 2041 and exclusivity 12 May 2029. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

5-methyl-2-phenyl-4H-pyrazol-3-one

Canonical SMILES

CC1=NN(C(=O)C1)C2=CC=CC=C2

InChIKey

QELUYTUMUWHWMC-UHFFFAOYSA-N