Duvelisib

Overview

Duvelisib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3039502).

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Duvelisib expires 26 Apr 2035. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

8-chloro-2-phenyl-3-[(1S)-1-(7H-purin-6-ylamino)ethyl]isoquinolin-1-one

Canonical SMILES

C[C@@H](C1=CC2=C(C(=CC=C2)Cl)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5

InChIKey

SJVQHLPISAIATJ-ZDUSSCGKSA-N