Duloxetine

Overview

Duloxetine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1175).

API suppliers (29)

Suppliers of Duloxetine evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• Lupin LimitedIndia2 active DMF GMP on record
• Alembic Pharmaceuticals LimitedIndia2 active DMF GMP on record
• MSN Laboratories Private LimitedIndia2 active DMF GMP on record
• SHANKUS PHARMA PRIVATE LTDIndia2 active DMF
• APITORIA PHARMA PRIVATE LTDIndia2 active DMF GMP on record
• Ipca Laboratories LimitedIndia1 active DMF GMP on record
• SHODHANA LABORATORIES PRIVATE LTD1 active DMF
• TAPI NL BVNetherlands1 active DMF
• SIGNA SA DE CV1 active DMF
• MATRIX PHARMACORP PRIVATE LTDIndia1 active DMF
• Zhejiang Huahai Pharmaceutical Co., Ltd.China1 active DMF GMP on record
• Torrent PharmaceuticalsIndia1 active DMF GMP on record
• HEC Pharm USA Inc.United States1 active DMF
• Wockhardt UsaUnited Kingdom1 active DMF
• Zydus Lifesciences LimitedIndia1 active DMF GMP on record
• ORBION PHARMACEUTICALS PRIVATE LTDIndia1 active DMF GMP on record
• Sun Pharmaceutical Industries LimitedIndia1 active DMF GMP on record
• Macleods Pharmaceuticals Ltd.India1 active DMF GMP on record
• Zhejiang Yongtai Pharmaceutical Co., Ltd.China1 active DMF
• Ajanta Pharma LimitedIndia1 active DMF
• ERREGIERRE SPAItaly GMP on record
• CHONGQING SHENGHUAXI PHARMACEUTICAL CO LTD
• RANBAXY LABORATORIES LTD
• Cadila Healthcare LimitedIndia
• SCI PHARMTECH INCTaiwan

Showing 25 of 29 suppliers — see the full list in the app.

Patent & exclusivity (US)

Per the FDA Orange Book (59 approved US products), the latest listed US patent on Duloxetine expires 13 Apr 2037. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine

Canonical SMILES

CNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=CC=CC=C32

InChIKey

ZEUITGRIYCTCEM-KRWDZBQOSA-N