Doxepin

CAS 1668-19-5 5 API suppliersSmall Molecule

Overview

Doxepin is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1628227).

API suppliers (5)

Suppliers of Doxepin evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

Where these suppliers are
India2Netherlands1

Country recorded for 3 of 5 suppliers.

1 of 5 holds a GMP certificate on record in the EU or UK registers

  • TAPI NL BVNetherlands1 active DMF
  • MSN LIFE SCIENCES PRIVATE LIMITEDIndia1 active DMF GMP on record
  • RAKS PHARMA PVT LTDIndia1 active DMF
  • BOEHRINGER MANNHEIM GMBH
  • SUMIKA FINE CHEMICALS CO LTD

Patent & exclusivity (US)

Per the FDA Orange Book (106 approved US products), the latest listed US patent on Doxepin expires 7 Sept 2030. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
3-(6H-benzo[c][1]benzoxepin-11-ylidene)-N,N-dimethylpropan-1-amine
Canonical SMILES
CN(C)CCC=C1C2=CC=CC=C2COC3=CC=CC=C31
InChIKey
ODQWQRRAPPTVAG-UHFFFAOYSA-N
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