Donepezil

Overview

Donepezil is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL502).

API suppliers (45)

Suppliers of Donepezil backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• Zydus Lifesciences LimitedIndia2 active DMF
• Hetero Drugs LimitedIndia2 active DMF
• Sun Pharmaceutical Industries LimitedIndia1 active DMF
• USV PRIVATE LTD1 active DMF
• Cipla USA, Inc.USA1 active DMF
• JUBILANT BIOSYS LTD1 active DMF
• Zhejiang Huahai Pharmaceutical Co., Ltd.China1 active DMF
• Sun Pharmaceutical Industries LimitedIndia1 active DMF
• Torrent PharmaceuticalsIndia1 active DMF
• Neuland Laboratories LimitedIndia1 active DMF
• Sun Pharmaceutical Industries LimitedIndia1 active DMF
• Alembic Pharmaceuticals LimitedIndia1 active DMF
• USV PRIVATE LTD1 active DMF
• JUBILANT BIOSYS LTD1 active DMF
• Cipla USA, Inc.USA1 active DMF
• Sun Pharmaceutical Industries LimitedIndia1 active DMF
• Dr. Reddy's Laboratories Ltd.India1 active DMF
• JUBILANT BIOSYS LTD1 active DMF
• USV PRIVATE LTD1 active DMF
• SYNTHOKEM LABS PRIVATE LTDIndia1 active DMF
• Zhejiang Huahai Pharmaceutical Co., Ltd.China1 active DMF
• APITORIA PHARMA PRIVATE LTDIndia1 active DMF
• Torrent PharmaceuticalsIndia1 active DMF
• Neuland Laboratories LimitedIndia1 active DMF
• VASUDHA PHARMA CHEM LTD1 active DMF

Showing 25 of 45 suppliers — see the full list in the app.

Patent & exclusivity (US)

Per the FDA Orange Book (44 approved US products), the latest listed US patent on Donepezil expires 3 Oct 2026. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one

Canonical SMILES

COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC

InChIKey

ADEBPBSSDYVVLD-UHFFFAOYSA-N