Docetaxel Anhydrous

CAS 114977-28-5 29 API suppliersSmall Molecule

Overview

Docetaxel Anhydrous is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL92).

API suppliers (29)

Suppliers of Docetaxel Anhydrous evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

Where these suppliers are
China8India6Taiwan1Italy1United States1Netherlands1Canada1United Kingdom1

Country recorded for 21 of 29 suppliers.

15 of 29 hold a GMP certificate on record in the EU or UK registers

Showing 25 of 29 suppliers — see the full list in the app.

Patent & exclusivity (US)

Per the FDA Orange Book (55 approved US products), the latest listed US patent on Docetaxel Anhydrous expires 16 May 2036. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,9,12-trihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
Canonical SMILES
CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O
InChIKey
ZDZOTLJHXYCWBA-VCVYQWHSSA-N
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