Docetaxel Anhydrous

Overview

Docetaxel Anhydrous is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL92).

API suppliers (8)

Suppliers of Docetaxel Anhydrous backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• Dr. Reddy's Laboratories Ltd.India1 active DMF
• Kisun Pharmaceutical Co., Ltd.China1 active DMF
• PHYTON BIOTECH LLC1 active DMF
• Kisun Pharmaceutical Co., Ltd.China1 active DMF
• Kisun Pharmaceutical Co., Ltd.China1 active DMF
• PHYTON BIOTECH LLC1 active DMF
• BENZOCHEM LIFESCIENCES PVT LTD
• SAMYANG HOLDINGS CORP

Patent & exclusivity (US)

Per the FDA Orange Book (55 approved US products), the latest listed US patent on Docetaxel Anhydrous expires 15 May 2036. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,9,12-trihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate

Canonical SMILES

CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

InChIKey

ZDZOTLJHXYCWBA-VCVYQWHSSA-N