Diazepam

Overview

Diazepam is a benzodiazepine that enhances the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, producing sedative and anxiolytic effects. It is commonly used to treat anxiety, muscle spasms, and seizures.

API suppliers (9)

Suppliers of Diazepam backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• CAMBREX PROFARMACO MILANO SRLItaly1 active DMF
• FIS FABBRICA ITALIANA SINTETICI SPA1 active DMF
• CAMBREX PROFARMACO MILANO SRLItaly1 active DMF
• FIS FABBRICA ITALIANA SINTETICI SPA1 active DMF
• CAMBREX PROFARMACO MILANO SRLItaly1 active DMF
• CENTAUR PHARMACEUTICALS PVT LTDIndia1 active DMF
• CENTAUR PHARMACEUTICALS PVT LTDIndia1 active DMF
• Gedeon RichterHungary
• DELMAR CHEMICALS INCCanada

Patent & exclusivity (US)

Per the FDA Orange Book (44 approved US products), the latest listed US patent on Diazepam expires 9 Jun 2042 and exclusivity 14 Apr 2028. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

7-chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2-one

Canonical SMILES

CN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3

InChIKey

AAOVKJBEBIDNHE-UHFFFAOYSA-N

Therapeutic areas